Assay
Age
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Western blot
Postnatal
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Pak2 p21 (RAC1) activated kinase 2 (Synonyms: 5330420P17Rik, A130002K10Rik, D16Ertd269e, PAK-2) | |
Results | Reference |
1 | J:143322 Chen Y, Stump RJ, Lovicu FJ, Shimono A, McAvoy JW, Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Dev Biol. 2008 Dec 1;324(1):161-76 |
1* | J:158222 Demyanenko GP, Halberstadt AI, Rao RS, Maness PF, CHL1 cooperates with PAK1-3 to regulate morphological differentiation of embryonic cortical neurons. Neuroscience. 2010 Jan 13;165(1):107-15 |
1* | J:303862 Hada K, Wulaer B, Nagai T, Itoh N, Sawahata M, Sobue A, Mizoguchi H, Mori D, Kushima I, Nabeshima T, Ozaki N, Yamada K, Mice carrying a schizophrenia-associated mutation of the Arhgap10 gene are vulnerable to the effects of methamphetamine treatment on cognitive function: association with morphological abnormalities in striatal neurons. Mol Brain. 2021 Jan 22;14(1):21 |
1 | J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579 |
1* | J:85956 Li X, Minden A, Targeted disruption of the gene for the PAK5 kinase in mice. Mol Cell Biol. 2003 Oct;23(20):7134-42 |
1 | J:294006 Rutkowski TP, Purcell RH, Pollak RM, Grewenow SM, Gafford GM, Malone T, Khan UA, Schroeder JP, Epstein MP, Bassell GJ, Warren ST, Weinshenker D, Caspary T, Mulle JG, Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion. Mol Psychiatry. 2019; |
1 | J:276133 Yang CY, Yu TH, Wen WL, Ling P, Hsu KS, Conditional Deletion of CC2D1A Reduces Hippocampal Synaptic Plasticity and Impairs Cognitive Function through Rac1 Hyperactivation. J Neurosci. 2019 Jun 19;39(25):4959-4975 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/14/2024 MGI 6.23 |
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